KDEL Receptors: Pathophysiological Functions, Therapeutic Options, and Biotechnological Opportunities

KDEL receptors (KDELRs) are ubiquitous seven-transmembrane domain proteins encoded by three mammalian genes. They bind to and retro-transport endoplasmic reticulum (ER)-resident proteins with a C-terminal Lys-Asp-Glu-Leu (KDEL) sequence or variants thereof. In doing this, KDELR participates in the E...

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Detalles Bibliográficos
Autores principales: Cela, Ilaria, Dufrusine, Beatrice, Rossi, Claudia, Luini, Alberto, De Laurenzi, Vincenzo, Federici, Luca, Sallese, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220330/
https://www.ncbi.nlm.nih.gov/pubmed/35740256
http://dx.doi.org/10.3390/biomedicines10061234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220330/
https://www.ncbi.nlm.nih.gov/pubmed/35740256
http://dx.doi.org/10.3390/biomedicines10061234

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