Evaluation of a Conformationally Constrained Indole Carboxamide as a Potential Efflux Pump Inhibitor in Pseudomonas aeruginosa

Efflux pumps in Gram-negative bacteria such as Pseudomonas aeruginosa provide intrinsic antimicrobial resistance by facilitating the extrusion of a wide range of antimicrobials. Approaches for combating efflux-mediated multidrug resistance involve, in part, developing indirect antimicrobial agents c...

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Detalles Bibliográficos
Autores principales: Zhang, Yongzheng, Rosado-Lugo, Jesus D., Datta, Pratik, Sun, Yangsheng, Cao, Yanlu, Banerjee, Anamika, Yuan, Yi, Parhi, Ajit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220351/
https://www.ncbi.nlm.nih.gov/pubmed/35740123
http://dx.doi.org/10.3390/antibiotics11060716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220351/
https://www.ncbi.nlm.nih.gov/pubmed/35740123
http://dx.doi.org/10.3390/antibiotics11060716

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