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Adipocyte-Specific Expression of PGC1α Promotes Adipocyte Browning and Alleviates Obesity-Induced Metabolic Dysfunction in an HO-1-Dependent Fashion

Recent studies suggest that PGC1-α plays a crucial role in mitochondrial and vascular function, yet the physiological significance of PGC1α and HO expression in adipose tissues in the context of obesity-linked vascular dysfunction remains unclear. We studied three groups of six-week-old C57BL/6J mal...

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Detalles Bibliográficos
Autores principales: Shen, Shin-Hsueh, Singh, Shailendra P., Raffaele, Marco, Waldman, Maayan, Hochhauser, Edith, Ospino, Juancarlos, Arad, Michael, Peterson, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220759/
https://www.ncbi.nlm.nih.gov/pubmed/35740043
http://dx.doi.org/10.3390/antiox11061147