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Immunization using ApoB-100 peptide–linked nanoparticles reduces atherosclerosis

Active immunization with the apolipoprotein B-100 (ApoB-100) peptide P210 reduces experimental atherosclerosis. To advance this immunization strategy to future clinical testing, we explored the possibility of delivering P210 as an antigen using nanoparticles, given this approach has been used clinic...

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Detalles Bibliográficos
Autores principales: Chyu, Kuang-Yuh, Zhao, Xiaoning, Zhou, Jianchang, Dimayuga, Paul C., Lio, Nicole W.M., Cercek, Bojan, Trac, Noah T., Chung, Eun Ji, Shah, Prediman K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220835/
https://www.ncbi.nlm.nih.gov/pubmed/35536648
http://dx.doi.org/10.1172/jci.insight.149741