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Immunization using ApoB-100 peptide–linked nanoparticles reduces atherosclerosis
Active immunization with the apolipoprotein B-100 (ApoB-100) peptide P210 reduces experimental atherosclerosis. To advance this immunization strategy to future clinical testing, we explored the possibility of delivering P210 as an antigen using nanoparticles, given this approach has been used clinic...
Autores principales: | Chyu, Kuang-Yuh, Zhao, Xiaoning, Zhou, Jianchang, Dimayuga, Paul C., Lio, Nicole W.M., Cercek, Bojan, Trac, Noah T., Chung, Eun Ji, Shah, Prediman K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220835/ https://www.ncbi.nlm.nih.gov/pubmed/35536648 http://dx.doi.org/10.1172/jci.insight.149741 |
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