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Photoinactivation of catalase sensitizes a wide range of bacteria to ROS-producing agents and immune cells

Bacteria have evolved to cope with the detrimental effects of ROS using their essential molecular components. Catalase, a heme-containing tetramer protein expressed universally in most aerobic bacteria, plays an indispensable role in scavenging excess hydrogen peroxide (H(2)O(2)). Here, through use...

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Detalles Bibliográficos
Autores principales: Dong, Pu-Ting, Jusuf, Sebastian, Hui, Jie, Zhan, Yuewei, Zhu, Yifan, Liu, George Y., Cheng, Ji-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220836/
https://www.ncbi.nlm.nih.gov/pubmed/35446788
http://dx.doi.org/10.1172/jci.insight.153079