Combination therapy with remdesivir and monoclonal antibodies protects nonhuman primates against advanced Sudan virus disease

A major challenge in managing acute viral infections is ameliorating disease when treatment is delayed. Previously, we reported the success of a 2-pronged mAb and antiviral remdesivir therapeutic approach to treat advanced illness in rhesus monkeys infected with Marburg virus (MARV). Here, we explor...

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Detalles Bibliográficos
Autores principales: Cross, Robert W., Bornholdt, Zachary A., Prasad, Abhishek N., Woolsey, Courtney, Borisevich, Viktoriya, Agans, Krystle N., Deer, Daniel J., Abelson, Dafna M., Kim, Do H., Shestowsky, William S., Campbell, Lioudmila A., Bunyan, Elaine, Geisbert, Joan B., Dobias, Natalie S., Fenton, Karla A., Porter, Danielle P., Zeitlin, Larry, Geisbert, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220838/
https://www.ncbi.nlm.nih.gov/pubmed/35413016
http://dx.doi.org/10.1172/jci.insight.159090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220838/
https://www.ncbi.nlm.nih.gov/pubmed/35413016
http://dx.doi.org/10.1172/jci.insight.159090

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