Linked sensitization by memory CD4(+) T cells prevents costimulation blockade–induced transplantation tolerance

Dominant infectious tolerance explains how brief tolerance-inducing therapies result in lifelong tolerance to donor antigens and “linked” third-party antigens, while recipient sensitization and ensuing immunological memory prevent the successful induction of transplant tolerance. In this study, we j...

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Detalles Bibliográficos
Autores principales: Andrade, Michael S., Young, James S., Pollard, Jared M., Yin, Dengping, Alegre, Maria-Luisa, Chong, Anita S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220839/
https://www.ncbi.nlm.nih.gov/pubmed/35674134
http://dx.doi.org/10.1172/jci.insight.159205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220839/
https://www.ncbi.nlm.nih.gov/pubmed/35674134
http://dx.doi.org/10.1172/jci.insight.159205

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