Cargando…
Linked sensitization by memory CD4(+) T cells prevents costimulation blockade–induced transplantation tolerance
Dominant infectious tolerance explains how brief tolerance-inducing therapies result in lifelong tolerance to donor antigens and “linked” third-party antigens, while recipient sensitization and ensuing immunological memory prevent the successful induction of transplant tolerance. In this study, we j...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220839/ https://www.ncbi.nlm.nih.gov/pubmed/35674134 http://dx.doi.org/10.1172/jci.insight.159205 |