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A Novel Proteogenomic Integration Strategy Expands the Breadth of Neo-Epitope Sources
SIMPLE SUMMARY: Tumor-specific antigens are ideal targets for cancer immunotherapy. Mass spectrometry, which is the main method that directly identifies neo-epitopes presented on tumor cells, focuses mainly on peptides derived from annotated protein-coding exomes. However, non-canonical peptides ari...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220843/ https://www.ncbi.nlm.nih.gov/pubmed/35740681 http://dx.doi.org/10.3390/cancers14123016 |