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A Novel Proteogenomic Integration Strategy Expands the Breadth of Neo-Epitope Sources

SIMPLE SUMMARY: Tumor-specific antigens are ideal targets for cancer immunotherapy. Mass spectrometry, which is the main method that directly identifies neo-epitopes presented on tumor cells, focuses mainly on peptides derived from annotated protein-coding exomes. However, non-canonical peptides ari...

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Detalles Bibliográficos
Autores principales: Xiang, Haitao, Zhang, Le, Bu, Fanyu, Guan, Xiangyu, Chen, Lei, Zhang, Haibo, Zhao, Yuntong, Chen, Huanyi, Zhang, Weicong, Li, Yijian, Lee, Leo Jingyu, Mei, Zhanlong, Rao, Yuan, Gu, Ying, Hou, Yong, Mu, Feng, Dong, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220843/
https://www.ncbi.nlm.nih.gov/pubmed/35740681
http://dx.doi.org/10.3390/cancers14123016