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RIP3 Translocation into Mitochondria Promotes Mitofilin Degradation to Increase Inflammation and Kidney Injury after Renal Ischemia–Reperfusion

The receptor-interacting protein kinase 3 (RIP3) has been reported to regulate programmed necrosis–necroptosis forms of cell death with important functions in inflammation. We investigated whether RIP3 translocates into mitochondria in response to renal ischemia–reperfusion (I/R) to interact with in...

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Detalles Bibliográficos
Autores principales: Feng, Yansheng, Imam Aliagan, Abdulhafiz, Tombo, Nathalie, Draeger, Derrick, Bopassa, Jean C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220894/
https://www.ncbi.nlm.nih.gov/pubmed/35741025
http://dx.doi.org/10.3390/cells11121894