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T cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibodies and disease severity

BACKGROUND: Measuring the immune response to SARS-CoV-2 enables assessment of past infection and protective immunity. SARS-CoV-2 infection induces humoral and T cell responses, but these responses vary with disease severity and individual characteristics. METHODS: A T cell receptor (TCR) immunoseque...

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Detalles Bibliográficos
Autores principales: Elyanow, Rebecca, Snyder, Thomas M., Dalai, Sudeb C., Gittelman, Rachel M., Boonyaratanakornkit, Jim, Wald, Anna, Selke, Stacy, Wener, Mark H., Morishima, Chihiro, Greninger, Alexander L., Gale, Michael, Hsiang, Tien-Ying, Jing, Lichen, Holbrook, Michael R., Kaplan, Ian M., Zahid, H. Jabran, May, Damon H., Carlson, Jonathan M., Baldo, Lance, Manley, Thomas, Robins, Harlan S., Koelle, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220924/
https://www.ncbi.nlm.nih.gov/pubmed/35439166
http://dx.doi.org/10.1172/jci.insight.150070