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Sine oculis homeobox homolog 1 plays a critical role in pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal disease with limited treatment options. The role of the developmental transcription factor Sine oculis homeobox homolog 1 (SIX1) in the pathophysiology of lung fibrosis is not known. IPF lung tissue samples and IPF-derived alveolar type II cells (AT2) s...

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Detalles Bibliográficos
Autores principales: Wilson, Cory, Mertens, Tinne C.J., Shivshankar, Pooja, Bi, Weizen, Collum, Scott D., Wareing, Nancy, Ko, Junsuk, Weng, Tingting, Naikawadi, Ram P., Wolters, Paul J., Maire, Pascal, Jyothula, Soma S.K., Thandavarayan, Rajarajan A., Ren, Dewei, Elrod, Nathan D., Wagner, Eric J., Huang, Howard J., Dickey, Burton F., Ford, Heide L., Karmouty-Quintana, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220956/
https://www.ncbi.nlm.nih.gov/pubmed/35420997
http://dx.doi.org/10.1172/jci.insight.142984