Sulfonamide-Derived Dithiocarbamate Gold(I) Complexes Induce the Apoptosis of Colon Cancer Cells by the Activation of Caspase 3 and Redox Imbalance

Two new families of dithiocarbamate gold(I) complexes derived from benzenesulfonamide with phosphine or carbene as ancillary ligands have been synthesized and characterized. In the screening of their in vitro activity on human colon carcinoma cells (Caco-2), we found that the more lipophilic complex...

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Detalles Bibliográficos
Autores principales: Quero, Javier, Royo, José Carlos, Fodor, Beatrice, Gimeno, María Concepción, Osada, Jesús, Rodríguez-Yoldi, María Jesús, Cerrada, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221018/
https://www.ncbi.nlm.nih.gov/pubmed/35740458
http://dx.doi.org/10.3390/biomedicines10061437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221018/
https://www.ncbi.nlm.nih.gov/pubmed/35740458
http://dx.doi.org/10.3390/biomedicines10061437

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