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Decoding the PITX2-controlled genetic network in atrial fibrillation

Atrial fibrillation (AF), the most common sustained cardiac arrhythmia and a major risk factor for stroke, often arises through ectopic electrical impulses derived from the pulmonary veins (PVs). Sequence variants in enhancers controlling expression of the transcription factor PITX2, which is expres...

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Detalles Bibliográficos
Autores principales: Steimle, Jeffrey D., Grisanti Canozo, Francisco J., Park, Minjun, Kadow, Zachary A., Samee, Md. Abul Hassan, Martin, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221021/
https://www.ncbi.nlm.nih.gov/pubmed/35471998
http://dx.doi.org/10.1172/jci.insight.158895