Super-Enhancers, Phase-Separated Condensates, and 3D Genome Organization in Cancer

SIMPLE SUMMARY: Gene expression is primarily controlled at the level of transcription, largely due to binding of transcription factors to specific sites on DNA, namely super-enhancers and promoters. Super-enhancers and enhancers can regulate distal target genes via chromatin looping mechanisms. Thes...

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Detalles Bibliográficos
Autores principales: Tang, Seng Chuan, Vijayakumar, Udhaya, Zhang, Ying, Fullwood, Melissa Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221043/
https://www.ncbi.nlm.nih.gov/pubmed/35740532
http://dx.doi.org/10.3390/cancers14122866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221043/
https://www.ncbi.nlm.nih.gov/pubmed/35740532
http://dx.doi.org/10.3390/cancers14122866

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