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Super-Enhancers, Phase-Separated Condensates, and 3D Genome Organization in Cancer
SIMPLE SUMMARY: Gene expression is primarily controlled at the level of transcription, largely due to binding of transcription factors to specific sites on DNA, namely super-enhancers and promoters. Super-enhancers and enhancers can regulate distal target genes via chromatin looping mechanisms. Thes...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221043/ https://www.ncbi.nlm.nih.gov/pubmed/35740532 http://dx.doi.org/10.3390/cancers14122866 |