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Modulating Microglia/Macrophage Activation by CDNF Promotes Transplantation of Fetal Ventral Mesencephalic Graft Survival and Function in a Hemiparkinsonian Rat Model

Parkinson’s disease (PD) is characterized by the loss of dopaminergic neurons in substantia nigra pars compacta, which leads to the motor control deficits. Recently, cell transplantation is a cutting-edge technique for the therapy of PD. Nevertheless, one key bottleneck to realizing such potential i...

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Detalles Bibliográficos
Autores principales: Tseng, Kuan-Yin, Wu, Jui-Sheng, Chen, Yuan-Hao, Airavaara, Mikko, Cheng, Cheng-Yi, Ma, Kuo-Hsing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221078/
https://www.ncbi.nlm.nih.gov/pubmed/35740467
http://dx.doi.org/10.3390/biomedicines10061446