BECLIN-1-Mediated Autophagy Suppresses Silica Nanoparticle-Induced Testicular Toxicity via the Inhibition of Caspase 8-Mediated Cell Apoptosis in Leydig Cells

Accumulation of silica nanoparticles (SNPs) in the testes leads to male reproductive toxicity. However, little is known about the effect and mechanistic insights of SNP-induced autophagy on apoptosis in Leydig cells. In this study, we aimed to verify the role of SNP-induced autophagy in apoptosis an...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qianru, Grunberger, Jason William, Khurana, Nitish, Zhou, Xin, Xu, Xianyu, Ghandehari, Hamidreza, Chen, Fenglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221084/
https://www.ncbi.nlm.nih.gov/pubmed/35740992
http://dx.doi.org/10.3390/cells11121863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221084/
https://www.ncbi.nlm.nih.gov/pubmed/35740992
http://dx.doi.org/10.3390/cells11121863

Ejemplares similares