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BECLIN-1-Mediated Autophagy Suppresses Silica Nanoparticle-Induced Testicular Toxicity via the Inhibition of Caspase 8-Mediated Cell Apoptosis in Leydig Cells
Accumulation of silica nanoparticles (SNPs) in the testes leads to male reproductive toxicity. However, little is known about the effect and mechanistic insights of SNP-induced autophagy on apoptosis in Leydig cells. In this study, we aimed to verify the role of SNP-induced autophagy in apoptosis an...
Autores principales: | Zhang, Qianru, Grunberger, Jason William, Khurana, Nitish, Zhou, Xin, Xu, Xianyu, Ghandehari, Hamidreza, Chen, Fenglei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221084/ https://www.ncbi.nlm.nih.gov/pubmed/35740992 http://dx.doi.org/10.3390/cells11121863 |
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