Deep Sequencing of Early T Stage Colorectal Cancers Reveals Disruption of Homologous Recombination Repair in Microsatellite Stable Tumours with High Mutational Burdens

SIMPLE SUMMARY: Stage IIIA are rare early T stage colorectal cancers that are not widely reported in genome sequencing studies. We aimed to investigate genomics features in common cancer genes associated with lymph node metastasis from these tumours. We discovered that microsatellite stable tumours...

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Detalles Bibliográficos
Autores principales: Li, Jun, Steffen, Pascal, Tse, Benita C. Y., Ahadi, Mahsa S., Gill, Anthony J., Engel, Alexander F., Molloy, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221133/
https://www.ncbi.nlm.nih.gov/pubmed/35740599
http://dx.doi.org/10.3390/cancers14122933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221133/
https://www.ncbi.nlm.nih.gov/pubmed/35740599
http://dx.doi.org/10.3390/cancers14122933

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