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Detection of DNA Methyltransferase Activity via Fluorescence Resonance Energy Transfer and Exonuclease-Mediated Target Recycling

In this study, a sensitive method for detecting DNA methyltransferase (MTase) activity was developed by combining the effective fluorescence resonance energy transfer (FRET) of cationic conjugated polymers and exonuclease (Exo) III–mediated signal amplification. DNA adenine MTase targets the GATC se...

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Detalles Bibliográficos
Autores principales: Hu, Tingting, Ma, Changbei, Yan, Ying, Chen, Junxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221148/
https://www.ncbi.nlm.nih.gov/pubmed/35735543
http://dx.doi.org/10.3390/bios12060395