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APOBEC Alteration Contributes to Tumor Growth and Immune Escape in Pan-Cancer

SIMPLE SUMMARY: The APOBEC3 family (apolipoprotein B mRNA editing enzyme catalytic polypeptide-like) was shown to induce tumor mutations through an aberrant DNA editing mechanism. In this study, we found that APOBEC genes were widely and significantly differentially expressed between normal and canc...

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Detalles Bibliográficos
Autores principales: Guo, Honghong, Zhu, Ling, Huang, Lu, Sun, Zhen, Zhang, Hui, Nong, Baoting, Xiong, Yuanyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221198/
https://www.ncbi.nlm.nih.gov/pubmed/35740493
http://dx.doi.org/10.3390/cancers14122827