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Attenuation of Muscle Damage, Structural Abnormalities, and Physical Activity in Respiratory and Limb Muscles following Treatment with Rucaparib in Lung Cancer Cachexia Mice

SIMPLE SUMMARY: Muscle wasting and cachexia are common in patients with cancer. Several mechanisms underlie muscle physiological and structural alterations in cancer-induced cachexia. Poly (ADPribose) polymerases (PARPs) are involved in muscle metabolism and in cancer. Selective inhibitors of PARP a...

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Detalles Bibliográficos
Autores principales: Pérez-Peiró, Maria, Duran, Xavier, Yélamos, José, Barreiro, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221243/
https://www.ncbi.nlm.nih.gov/pubmed/35740560
http://dx.doi.org/10.3390/cancers14122894