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Biodegradable Ultrasmall-in-Nano Architectures Loaded with Cisplatin Prodrug in Combination with Ionizing Radiation Induces DNA Damage and Apoptosis in Pancreatic Ductal Adenocarcinoma

SIMPLE SUMMARY: The occurrence of severe normal tissue side effects and acquired drug resistance of the malignancy are the most important limitations that are associated with currently given systemic treatment in pancreatic cancer. The aim of this study was to assess the therapeutic efficacy of enca...

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Detalles Bibliográficos
Autores principales: Che, Pei Pei, Mapanao, Ana Katrina, Gregori, Alessandro, Ermini, Maria Laura, Zamborlin, Agata, Capula, Mjriam, Ngadimin, Danitsja, Slotman, Ben J., Voliani, Valerio, Sminia, Peter, Giovannetti, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221262/
https://www.ncbi.nlm.nih.gov/pubmed/35740699
http://dx.doi.org/10.3390/cancers14123034