Midazolam as a Probe for Heterotropic Drug-Drug Interactions Mediated by CYP3A4

Human cytochrome P450 CYP3A4 is involved in the processing of more than 35% of current pharmaceuticals and therefore is responsible for multiple drug-drug interactions (DDI). In order to develop a method for the detection and prediction of the possible involvement of new drug candidates in CYP3A4-me...

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Detalles Bibliográficos
Autores principales: Denisov, Ilia G., Grinkova, Yelena V., McLean, Mark A., Camp, Tyler, Sligar, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221276/
https://www.ncbi.nlm.nih.gov/pubmed/35740978
http://dx.doi.org/10.3390/biom12060853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221276/
https://www.ncbi.nlm.nih.gov/pubmed/35740978
http://dx.doi.org/10.3390/biom12060853

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