Cargando…

Midazolam as a Probe for Heterotropic Drug-Drug Interactions Mediated by CYP3A4

Human cytochrome P450 CYP3A4 is involved in the processing of more than 35% of current pharmaceuticals and therefore is responsible for multiple drug-drug interactions (DDI). In order to develop a method for the detection and prediction of the possible involvement of new drug candidates in CYP3A4-me...

Descripción completa

Detalles Bibliográficos
Autores principales:	Denisov, Ilia G., Grinkova, Yelena V., McLean, Mark A., Camp, Tyler, Sligar, Stephen G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221276/ https://www.ncbi.nlm.nih.gov/pubmed/35740978 http://dx.doi.org/10.3390/biom12060853

Ejemplares similares

Biotransformation of the Mycotoxin Enniatin B1 by CYP P450 3A4 and Potential for Drug-Drug Interactions
por: Ivanova, Lada, et al.
Publicado: (2019)

Using the MWC model to describe heterotropic interactions in hemoglobin
por: Rapp, Olga, et al.
Publicado: (2017)

Nanodiscs as a therapeutic delivery agent: inhibition of respiratory syncytial virus infection in the lung
por: Numata, Mari, et al.
Publicado: (2013)

Successful management of post-in-vitro fertilization cervical heterotropic pregnancy
por: Majumdar, Abha, et al.
Publicado: (2009)

Pharmacokinetic Evaluation of CYP3A4‐Mediated Drug‐Drug Interactions of Isavuconazole With Rifampin, Ketoconazole, Midazolam, and Ethinyl Estradiol/Norethindrone in Healthy Adults
por: Townsend, Robert, et al.
Publicado: (2016)

Interaction between Fexofenadine and CYP Phenotyping Probe Drugs in Geneva Cocktail
por: Bosilkovska, Marija, et al.
Publicado: (2019)

Insights into CYP2B6-mediated drug–drug interactions
por: Hedrich, William D., et al.
Publicado: (2016)

Inhibition of CYP3A-mediated Midazolam Metabolism by Kaempferia Parviflora
por: Kashiwabuchi, Yumika, et al.
Publicado: (2022)

Physiologically‐Based Pharmacokinetic Models for CYP1A2 Drug–Drug Interaction Prediction: A Modeling Network of Fluvoxamine, Theophylline, Caffeine, Rifampicin, and Midazolam
por: Britz, Hannah, et al.
Publicado: (2019)

CYP‐mediated drug–drug interactions with evacetrapib, an investigational CETP inhibitor: in vitro prediction and clinical outcome
por: Cannady, Ellen A., et al.
Publicado: (2015)

Impact of Subacute Exposure to T-2 Toxin and Zearalenone on the Pharmacokinetics of Midazolam as CYP3A Probe Drug in a Porcine Animal Model: A Pilot Study
por: Schelstraete, Wim, et al.
Publicado: (2019)

Clinical evaluation of the potential drug–drug interactions of savolitinib: Interaction with rifampicin, itraconazole, famotidine or midazolam
por: Ren, Song, et al.
Publicado: (2021)

Pharmacokinetic drug interactions of asciminib with the sensitive cytochrome P450 probe substrates midazolam, warfarin, and repaglinide in healthy participants
por: Hoch, Matthias, et al.
Publicado: (2022)

Evidence of CYP3A Allosterism In Vivo: Analysis of Fluconazole and Midazolam Interaction
por: Yang, Jing, et al.
Publicado: (2011)

Heterotropic Effect of β-lactam Antibiotics on Antioxidant Property of Haptoglobin (2-2)-Hemoglobin Complex
por: Tayari, Masoumeh, et al.
Publicado: (2011)

A new heterotropic vascularized model of total urinary bladder transplantation in a rat model
por: Jundziłł, Arkadiusz, et al.
Publicado: (2021)

Amenamevir: Studies of Potential CYP3A‐Mediated Pharmacokinetic Interactions With Midazolam, Cyclosporine, and Ritonavir in Healthy Volunteers
por: Adeloye, Temitope, et al.
Publicado: (2018)

Midazolam: an essential palliative care drug
por: Prommer, Eric
Publicado: (2020)

The rare presentations of a large polyp and an esophageal carcinoma in heterotropic gastric mucosa: a case series
por: Alagozlu, Hakan, et al.
Publicado: (2007)

Structure of an Engineered β-Lactamase Maltose Binding Protein Fusion Protein: Insights into Heterotropic Allosteric Regulation
por: Ke, Wei, et al.
Publicado: (2012)

Heterotropic roles of divalent cations in the establishment of allostery and affinity maturation of integrin αXβ2
por: Manandhar, Pragya, et al.
Publicado: (2022)

Investigation into CYP3A4-mediated drug–drug interactions on midostaurin in healthy volunteers
por: Dutreix, Catherine, et al.
Publicado: (2013)

Evaluation of CYP3A‐mediated drug–drug interactions with romidepsin in patients with advanced cancer
por: Laille, Eric, et al.
Publicado: (2015)

Model‐based assessments of CYP3A‐mediated drug‐drug interaction risk of milademetan
por: Hong, Ying, et al.
Publicado: (2021)

In Vitro Assessment of CYP-Mediated Drug Interactions for Kinsenoside, an Antihyperlipidemic Candidate
por: Rehman, Shaheed Ur, et al.
Publicado: (2016)

Drug-drug interactions: it is not only CYP450's which matter
por: Back, David J
Publicado: (2010)

Effects of salidroside on rat CYP enzymes by a cocktail of probe drugs
por: Wei, Yan-Li, et al.
Publicado: (2018)

Inhibitory effects of Triphala on CYP isoforms in vitro and its pharmacokinetic interactions with phenacetin and midazolam in rats
por: Nontakham, Jannarin, et al.
Publicado: (2022)

Potential for Drug Repositioning of Midazolam for Dentin Regeneration
por: Karakida, Takeo, et al.
Publicado: (2019)

Evaluation of the CYP3A and CYP2B6 Drug‐Drug Interaction Potential of Lemborexant
por: Landry, Ishani, et al.
Publicado: (2021)

Semiphysiologically based pharmacokinetic model for midazolam and CYP3A mediated metabolite 1‐OH‐midazolam in morbidly obese and weight loss surgery patients
por: Brill, MJE, et al.
Publicado: (2015)

A clinical therapeutic protein drug–drug interaction study: coadministration of denosumab and midazolam in postmenopausal women with osteoporosis
por: Jang, Graham, et al.
Publicado: (2014)

Composite midazolam and 1′-OH midazolam population pharmacokinetic model for constitutive, inhibited and induced CYP3A activity
por: Wiebe, Sabrina T., et al.
Publicado: (2020)

Fluoxetine and norfluoxetine mediated complex drug-drug interactions: in vitro to in vivo correlation of effects on CYP2D6, CYP2C19 and CYP3A4
por: Sager, Jennifer E, et al.
Publicado: (2014)

Functional phenotyping of the CYP2D6 probe drug codeine in the horse
por: Gretler, S. R., et al.
Publicado: (2021)

Influence of Transmembrane Helix Mutations on Cytochrome P450-Membrane Interactions and Function
por: Mustafa, Ghulam, et al.
Publicado: (2019)

Evaluation of drug interaction potential of zanubrutinib with cocktail probes representative of CYP3A4, CYP2C9, CYP2C19, P‐gp and BCRP
por: Ou, Ying C., et al.
Publicado: (2021)

First‐Pass CYP3A‐Mediated Metabolism of Midazolam in the Gut Wall and Liver in Preterm Neonates
por: Brussee, Janneke M., et al.
Publicado: (2018)

Physiologically‐Based Pharmacokinetic Modeling for the Prediction of CYP2D6‐Mediated Gene–Drug–Drug Interactions
por: Storelli, Flavia, et al.
Publicado: (2019)

Physiologically‐based pharmacokinetic modeling to predict CYP3A4‐mediated drug‐drug interactions of finerenone
por: Wendl, Thomas, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_m9vba31n8qljqi9ibu2j95rr1b