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Hedgehog Morphogens Act as Growth Factors Critical to Pre- and Postnatal Cardiac Development and Maturation: How Primary Cilia Mediate Their Signal Transduction

Primary cilia are crucial for normal cardiac organogenesis via the formation of cyto-architectural, anatomical, and physiological boundaries in the developing heart and outflow tract. These tiny, plasma membrane-bound organelles function in a sensory-integrative capacity, interpreting both the intra...

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Detalles Bibliográficos
Autores principales: Fitzsimons, Lindsey A., Brewer, Victoria L., Tucker, Kerry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221318/
https://www.ncbi.nlm.nih.gov/pubmed/35741008
http://dx.doi.org/10.3390/cells11121879