Phosphatidylinositol Monophosphates Regulate the Membrane Localization of HSPA1A, a Stress-Inducible 70-kDa Heat Shock Protein

HSPA1A is a molecular chaperone that regulates the survival of stressed and cancer cells. In addition to its cytosolic pro-survival functions, HSPA1A also localizes and embeds in the plasma membrane (PM) of stressed and tumor cells. Membrane-associated HSPA1A exerts immunomodulatory functions and re...

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Detalles Bibliográficos
Autores principales: Smulders, Larissa, Altman, Rachel, Briseno, Carolina, Saatchi, Alireza, Wallace, Leslie, AlSebaye, Maha, Stahelin, Robert V., Nikolaidis, Nikolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221345/
https://www.ncbi.nlm.nih.gov/pubmed/35740982
http://dx.doi.org/10.3390/biom12060856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221345/
https://www.ncbi.nlm.nih.gov/pubmed/35740982
http://dx.doi.org/10.3390/biom12060856

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