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MAEL Augments Cancer Stemness Properties and Resistance to Sorafenib in Hepatocellular Carcinoma through the PTGS2/AKT/STAT3 Axis

SIMPLE SUMMARY: Hepatocellular cancer (HCC) is the most common and lethal subtype of liver cancer without effective therapeutics. Understanding and targeting cancer stem cells (CSCs), a stem-cell-like subpopulation, which are emerging as effective ways to decipher tumor biology and develop therapies...

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Detalles Bibliográficos
Autores principales: Shi, Chaoran, Kwong, Dora Lai-Wan, Li, Xue, Wang, Xia, Fang, Xiaona, Sun, Liangzhan, Tang, Ying, Guan, Xin-Yuan, Li, Shan-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221398/
https://www.ncbi.nlm.nih.gov/pubmed/35740546
http://dx.doi.org/10.3390/cancers14122880