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Thwarting of Lphn3 Functions in Cell Motility and Signaling by Cancer-Related GAIN Domain Somatic Mutations

Cancer progression relies on cellular transition states accompanied by changes in the functionality of adhesion molecules. The gene for adhesion G protein-coupled receptor latrophilin-3 (aGPCR Lphn3 or ADGRL3) is targeted by tumor-specific somatic mutations predominantly affecting the conserved GAIN...

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Detalles Bibliográficos
Autores principales: Avila-Zozaya, Monserrat, Rodríguez-Hernández, Brenda, Monterrubio-Ledezma, Feliciano, Cisneros, Bulmaro, Boucard, Antony A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221416/
https://www.ncbi.nlm.nih.gov/pubmed/35741042
http://dx.doi.org/10.3390/cells11121913