Cargando…

Thwarting of Lphn3 Functions in Cell Motility and Signaling by Cancer-Related GAIN Domain Somatic Mutations

Cancer progression relies on cellular transition states accompanied by changes in the functionality of adhesion molecules. The gene for adhesion G protein-coupled receptor latrophilin-3 (aGPCR Lphn3 or ADGRL3) is targeted by tumor-specific somatic mutations predominantly affecting the conserved GAIN...

Descripción completa

Detalles Bibliográficos
Autores principales:	Avila-Zozaya, Monserrat, Rodríguez-Hernández, Brenda, Monterrubio-Ledezma, Feliciano, Cisneros, Bulmaro, Boucard, Antony A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221416/ https://www.ncbi.nlm.nih.gov/pubmed/35741042 http://dx.doi.org/10.3390/cells11121913

Ejemplares similares

Rescue of Mitochondrial Function in Hutchinson-Gilford Progeria Syndrome by the Pharmacological Modulation of Exportin CRM1
por: Monterrubio-Ledezma, Feliciano, et al.
Publicado: (2023)

Latrophilins: A Neuro-Centric View of an Evolutionary Conserved Adhesion G Protein-Coupled Receptor Subfamily
por: Moreno-Salinas, Ana L., et al.
Publicado: (2019)

Random domain name and address mutation (RDAM) for thwarting reconnaissance attacks
por: Wang, Kai, et al.
Publicado: (2017)

Thwarting the Divine Will
Publicado: (1891)

Tissue Expression Of LPHN3 in Breast Cancer: An Immunohistochemistry Method
por: Kotepui, Kwuntida Uthaisar, et al.
Publicado: (2020)

ADGRL3 (LPHN3) variants predict substance use disorder
por: Arcos-Burgos, Mauricio, et al.
Publicado: (2019)

LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion
por: Camillo, Chiara, et al.
Publicado: (2021)

CircLphn3 protects the blood-brain barrier in traumatic brain injury
por: Cheng, Yu-Qi, et al.
Publicado: (2021)

How staph thwarts attack
por: Maxmen, Amy
Publicado: (2009)

A cooperative interaction between LPHN3 and 11q doubles the risk for ADHD
por: Jain, M, et al.
Publicado: (2012)

Behavioral and transcriptomic profiling of mice null for Lphn3, a gene implicated in ADHD and addiction
por: Orsini, Caitlin A., et al.
Publicado: (2016)

ADGRL3 (LPHN3) variants are associated with a refined phenotype of ADHD in the MTA study
por: Acosta, Maria T., et al.
Publicado: (2016)

Crystal structure of LRG1 and the functional significance of LRG1 glycan for LPHN2 activation
por: Yang, Jimin, et al.
Publicado: (2023)

CCR5 thwarts West Nile virus
por: Van Epps, Heather L.
Publicado: (2006)

Thwarting galectin-induced immunosuppression in breast cancer
por: Salatino, Mariana, et al.
Publicado: (2013)

Fireflies thwart bat attack with multisensory warnings
por: Leavell, Brian C., et al.
Publicado: (2018)

Impulsive choice in two different rat models of ADHD—Spontaneously hypertensive and Lphn3 knockout rats
por: Carbajal, Monica S., et al.
Publicado: (2023)

Aberrant Epigenetic Modifications of LPHN2 Function as a Potential Cisplatin-Specific Biomarker for Human Gastrointestinal Cancer
por: Jeon, Mi-Seong, et al.
Publicado: (2016)

The adhesion GPCRs CELSR1–3 and LPHN3 engage G proteins via distinct activation mechanisms
por: Bui, Duy Lan Huong, et al.
Publicado: (2023)

Misguiding cues used by HIV to thwart protective immunity
por: Reinherz, EL, et al.
Publicado: (2006)

Four erroneous beliefs thwarting more trustworthy research
por: Yarborough, Mark, et al.
Publicado: (2019)

Bacteriocins to Thwart Bacterial Resistance in Gram Negative Bacteria
por: Telhig, Soufiane, et al.
Publicado: (2020)

The tobacco industry’s thwarting of marketing restrictions and health warnings in Lebanon
por: Nakkash, R, et al.
Publicado: (2009)

Thwarting endogenous stress: BRCA protects against aldehyde toxicity
por: Ray Chaudhuri, Arnab, et al.
Publicado: (2017)

Quest for SARS source gathers pace in bid to thwart resurgence
por: Abbott, Alison
Publicado: (2003)

Gut Dysbiosis Thwarts the Efficacy of Vaccine Against Mycobacterium tuberculosis
por: Nadeem, Sajid, et al.
Publicado: (2020)

Advanced strategies to thwart foreign body response to implantable devices
por: Capuani, Simone, et al.
Publicado: (2022)

What Approaches to Thwart Bacterial Efflux Pumps-Mediated Resistance?
por: Seukep, Armel Jackson, et al.
Publicado: (2022)

Heterogeneity thwarts autism explanatory power: A proposal for endophenotypes
por: Waterhouse, Lynn
Publicado: (2022)

A two-locus genetic interaction between LPHN3 and 11q predicts ADHD severity and long-term outcome
por: Acosta, M T, et al.
Publicado: (2011)

Development of Multidrug Resistance in Acute Myeloid Leukemia Is Associated with Alterations of the LPHN1/GAL-9/TIM-3 Signaling Pathway
por: Kocibalova, Zuzana, et al.
Publicado: (2021)

Diagnosing Nodular Regenerative Hyperplasia of the Liver Is Thwarted by Low Interobserver Agreement
por: Jharap, Bindia, et al.
Publicado: (2015)

Immune surveillance is thwarted by tumor-cell intrinsic beta-catenin signaling
por: Spranger, Stefani, et al.
Publicado: (2015)

Influenza Hemagglutinin and Neuraminidase: Yin–Yang Proteins Coevolving to Thwart Immunity
por: Kosik, Ivan, et al.
Publicado: (2019)

Thwarting Alzheimer’s Disease through Healthy Lifestyle Habits: Hope for the Future
por: Govindugari, Vijaya Laxmi, et al.
Publicado: (2023)

Domain landscapes of somatic mutations in cancer
por: Nehrt, Nathan L, et al.
Publicado: (2012)

Nuclear protein export pathway in aging therapeutics
por: Cisneros, Bulmaro, et al.
Publicado: (2020)

Thwarting science by protecting the received wisdom on tobacco addiction from the scientific method
por: DiFranza, Joseph R
Publicado: (2010)

Can Mixed Parasite Infections Thwart Targeted Malaria Elimination Program in India?
por: Singh, Upasana Shyamsunder, et al.
Publicado: (2017)

Gene-drive-mediated extinction is thwarted by population structure and evolution of sib mating
por: Bull, James J, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_fbsrk2r949gheijerju6tdoiut