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The Spike Protein of SARS-CoV-2 Impairs Lipid Metabolism and Increases Susceptibility to Lipotoxicity: Implication for a Role of Nrf2

Coronavirus disease 2019 (COVID-19) patients show lipid metabolic alterations, but the mechanism remains unknown. In this study, we aimed to investigate whether the Spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) impairs lipid metabolism in host cells. We generated a Sp...

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Detalles Bibliográficos
Autores principales: Nguyen, Vi, Zhang, Yuping, Gao, Chao, Cao, Xiaoling, Tian, Yan, Carver, Wayne, Kiaris, Hippokratis, Cui, Taixing, Tan, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221434/
https://www.ncbi.nlm.nih.gov/pubmed/35741045
http://dx.doi.org/10.3390/cells11121916