Cargando…

Unraveling the Biology of Epithelioid Hemangioendothelioma, a TAZ–CAMTA1 Fusion Driven Sarcoma

SIMPLE SUMMARY: Epithelioid hemangioendothelioma (EHE) is a rare vascular cancer that involves a gain-of-function gene fusion involving TAZ, a transcriptional coactivator, and one of two end effectors of the Hippo pathway. Although the activity of TAZ and/or YAP, a paralog of TAZ, is consistently al...

Descripción completa

Detalles Bibliográficos
Autores principales: Seavey, Caleb N., Pobbati, Ajaybabu V., Rubin, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221450/
https://www.ncbi.nlm.nih.gov/pubmed/35740643
http://dx.doi.org/10.3390/cancers14122980