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Integrated Drug Mining Reveals Actionable Strategies Inhibiting Plexiform Neurofibromas

Neurofibromatosis Type 1 (NF1) is one of the most common genetic tumor predisposition syndromes, affecting up to 1 in 2500 individuals. Up to half of patients with NF1 develop benign nerve sheath tumors called plexiform neurofibromas (PNs), characterized by biallelic NF1 loss. PNs can grow to immens...

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Detalles Bibliográficos
Autores principales: Brown, Rebecca M., Farouk Sait, Sameer, Dunn, Griffin, Sullivan, Alanna, Bruckert, Benjamin, Sun, Daochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221468/
https://www.ncbi.nlm.nih.gov/pubmed/35741605
http://dx.doi.org/10.3390/brainsci12060720