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Synthetic Vulnerabilities in the KRAS Pathway

SIMPLE SUMMARY: Despite recent dramatic progress, developing drugs that target oncogenic KRAS or its key effectors remains a major challenge for cancer research. Improving our understanding of the underlying biology of KRAS in cancer will identify potential codependent vulnerabilities or synthetic l...

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Detalles Bibliográficos
Autores principales: Roman, Marta, Hwang, Elizabeth, Sweet-Cordero, E. Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221492/
https://www.ncbi.nlm.nih.gov/pubmed/35740503
http://dx.doi.org/10.3390/cancers14122837