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Bone Marrow Fibrosis at Diagnosis and during the Course of Disease Is Associated with TP53 Mutations and Adverse Prognosis in Primary Myelodysplastic Syndrome

SIMPLE SUMMARY: To understand the role of bone marrow fibrosis and its molecular changes in myelodysplastic syndrome, we retrospectively analyzed data from 814 patients. Older age, lower hemoglobin, unfavorable karyotype and higher BM blast were more often observed in patients with moderate/severe f...

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Detalles Bibliográficos
Autores principales: Zhao, Youshan, Guo, Juan, Zhao, Sida, Wang, Roujia, Shi, Lei, Fang, Ying, Zhang, Zheng, Song, Luxi, Wu, Dong, Chang, Chunkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221530/
https://www.ncbi.nlm.nih.gov/pubmed/35740649
http://dx.doi.org/10.3390/cancers14122984