Unique SMYD5 Structure Revealed by AlphaFold Correlates with Its Functional Divergence

SMYD5 belongs to a special class of protein lysine methyltransferases with an MYND (Myeloid-Nervy-DEAF1) domain inserted into a SET (Suppressor of variegation, Enhancer of Zeste, Trithorax) domain. Despite recent advances in its functional characterization, the lack of the crystal structure has hind...

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Detalles Bibliográficos
Autores principales: Zhang, Yingxue, Alshammari, Eid, Sobota, Jacob, Yang, Alexander, Li, Chunying, Yang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221539/
https://www.ncbi.nlm.nih.gov/pubmed/35740908
http://dx.doi.org/10.3390/biom12060783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221539/
https://www.ncbi.nlm.nih.gov/pubmed/35740908
http://dx.doi.org/10.3390/biom12060783

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