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Flow Cytometric Detection of Malignant Blasts in Cerebrospinal Fluid: A Biomarker of Central Nervous System Involvement in Childhood Acute Lymphoblastic Leukemia

Despite the excellent prognosis for children and adolescents with acute lymphoblastic lymphoma (ALL), the involvement of the central nervous system (CNS) represents a major therapeutic challenge. Patients who develop CNS relapse have a very poor prognosis, and since current methods cannot reliably i...

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Detalles Bibliográficos
Autores principales: Thastrup, Maria, Marquart, Hanne Vibeke, Schmiegelow, Kjeld
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221543/
https://www.ncbi.nlm.nih.gov/pubmed/35740938
http://dx.doi.org/10.3390/biom12060813