Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer

Despite early studies linking calcium-calmodulin protein kinase kinase 2 (CAMKK2) to prostate cancer cell migration and invasion, the role of CAMKK2 in metastasis in vivo remains unclear. Moreover, while CAMKK2 is known to regulate systemic metabolism, whether CAMKK2’s effects on whole-body metaboli...

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Detalles Bibliográficos
Autores principales: Pulliam, Thomas L., Awad, Dominik, Han, Jenny J., Murray, Mollianne M., Ackroyd, Jeffrey J., Goli, Pavithr, Oakhill, Jonathan S., Scott, John W., Ittmann, Michael M., Frigo, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221545/
https://www.ncbi.nlm.nih.gov/pubmed/35741020
http://dx.doi.org/10.3390/cells11121890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221545/
https://www.ncbi.nlm.nih.gov/pubmed/35741020
http://dx.doi.org/10.3390/cells11121890

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