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The Senescence Markers p16INK4A, p14ARF/p19ARF, and p21 in Organ Development and Homeostasis

It is widely accepted that senescent cells accumulate with aging. They are characterized by replicative arrest and the release of a myriad of factors commonly called the senescence-associated secretory phenotype. Despite the replicative cell cycle arrest, these cells are metabolically active and fun...

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Detalles Bibliográficos
Autores principales: Wagner, Kay-Dietrich, Wagner, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221567/
https://www.ncbi.nlm.nih.gov/pubmed/35741095
http://dx.doi.org/10.3390/cells11121966