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Telomere Maintenance and the cGAS-STING Pathway in Cancer

Cancer cells exhibit the unique characteristics of high proliferation and aberrant DNA damage response, which prevents cancer therapy from effectively eliminating them. The machinery required for telomere maintenance, such as telomerase and the alternative lengthening of telomeres (ALT), enables can...

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Detalles Bibliográficos
Autores principales: Ebata, Hiroshi, Loo, Tze Mun, Takahashi, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221635/
https://www.ncbi.nlm.nih.gov/pubmed/35741087
http://dx.doi.org/10.3390/cells11121958