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Autocrine Activity of Extracellular Vesicles Induced by Icariin and Its Effectiveness in Glucocorticoid-Induced Injury of Bone Microvascular Endothelial Cells

Glucocorticoids could induce injury and apoptosis of bone microvascular endothelial cells (BMECs) in the femoral head, which is associated with the development of osteonecrosis and osteoporosis. Icariin is a prenylated flavonol glycoside isolated from Epimedium brevicornum, serving as the main activ...

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Detalles Bibliográficos
Autores principales: Zhang, Qingyu, Li, Tengqi, Li, Zirong, Lu, Jike, Wu, Xinjie, Gao, Fuqiang, Sun, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221798/
https://www.ncbi.nlm.nih.gov/pubmed/35741052
http://dx.doi.org/10.3390/cells11121921