Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review
Metastases are the main type of malignancy involving bone, which is the third most frequent site of metastatic carcinoma, after lung and liver. Skeletal-related events such as intractable pain, spinal cord compression, and pathologic fractures pose a serious burden on patients’ quality of life. For...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221897/ https://www.ncbi.nlm.nih.gov/pubmed/35735441 http://dx.doi.org/10.3390/curroncol29060332 |
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author | Papalexis, Nicolas Parmeggiani, Anna Peta, Giuliano Spinnato, Paolo Miceli, Marco Facchini, Giancarlo |
author_facet | Papalexis, Nicolas Parmeggiani, Anna Peta, Giuliano Spinnato, Paolo Miceli, Marco Facchini, Giancarlo |
author_sort | Papalexis, Nicolas |
collection | PubMed |
description | Metastases are the main type of malignancy involving bone, which is the third most frequent site of metastatic carcinoma, after lung and liver. Skeletal-related events such as intractable pain, spinal cord compression, and pathologic fractures pose a serious burden on patients’ quality of life. For this reason, mini-invasive treatments for the management of bone metastases were developed with the goal of pain relief and functional status improvement. These techniques include embolization, thermal ablation, electrochemotherapy, cementoplasty, and MRI-guided high-intensity focused ultrasound. In order to achieve durable pain palliation and disease control, mini-invasive procedures are combined with chemotherapy, radiation therapy, surgery, or analgesics. The purpose of this review is to summarize the recently published literature regarding interventional radiology procedures in the treatment of cancer patients with bone metastases, focusing on the efficacy, complications, local disease control and recurrence rate. |
format | Online Article Text |
id | pubmed-9221897 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92218972022-06-24 Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review Papalexis, Nicolas Parmeggiani, Anna Peta, Giuliano Spinnato, Paolo Miceli, Marco Facchini, Giancarlo Curr Oncol Review Metastases are the main type of malignancy involving bone, which is the third most frequent site of metastatic carcinoma, after lung and liver. Skeletal-related events such as intractable pain, spinal cord compression, and pathologic fractures pose a serious burden on patients’ quality of life. For this reason, mini-invasive treatments for the management of bone metastases were developed with the goal of pain relief and functional status improvement. These techniques include embolization, thermal ablation, electrochemotherapy, cementoplasty, and MRI-guided high-intensity focused ultrasound. In order to achieve durable pain palliation and disease control, mini-invasive procedures are combined with chemotherapy, radiation therapy, surgery, or analgesics. The purpose of this review is to summarize the recently published literature regarding interventional radiology procedures in the treatment of cancer patients with bone metastases, focusing on the efficacy, complications, local disease control and recurrence rate. MDPI 2022-06-07 /pmc/articles/PMC9221897/ /pubmed/35735441 http://dx.doi.org/10.3390/curroncol29060332 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Papalexis, Nicolas Parmeggiani, Anna Peta, Giuliano Spinnato, Paolo Miceli, Marco Facchini, Giancarlo Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review |
title | Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review |
title_full | Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review |
title_fullStr | Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review |
title_full_unstemmed | Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review |
title_short | Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review |
title_sort | minimally invasive interventional procedures for metastatic bone disease: a comprehensive review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221897/ https://www.ncbi.nlm.nih.gov/pubmed/35735441 http://dx.doi.org/10.3390/curroncol29060332 |
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