Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review

Metastases are the main type of malignancy involving bone, which is the third most frequent site of metastatic carcinoma, after lung and liver. Skeletal-related events such as intractable pain, spinal cord compression, and pathologic fractures pose a serious burden on patients’ quality of life. For...

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Autores principales: Papalexis, Nicolas, Parmeggiani, Anna, Peta, Giuliano, Spinnato, Paolo, Miceli, Marco, Facchini, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221897/
https://www.ncbi.nlm.nih.gov/pubmed/35735441
http://dx.doi.org/10.3390/curroncol29060332
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author Papalexis, Nicolas
Parmeggiani, Anna
Peta, Giuliano
Spinnato, Paolo
Miceli, Marco
Facchini, Giancarlo
author_facet Papalexis, Nicolas
Parmeggiani, Anna
Peta, Giuliano
Spinnato, Paolo
Miceli, Marco
Facchini, Giancarlo
author_sort Papalexis, Nicolas
collection PubMed
description Metastases are the main type of malignancy involving bone, which is the third most frequent site of metastatic carcinoma, after lung and liver. Skeletal-related events such as intractable pain, spinal cord compression, and pathologic fractures pose a serious burden on patients’ quality of life. For this reason, mini-invasive treatments for the management of bone metastases were developed with the goal of pain relief and functional status improvement. These techniques include embolization, thermal ablation, electrochemotherapy, cementoplasty, and MRI-guided high-intensity focused ultrasound. In order to achieve durable pain palliation and disease control, mini-invasive procedures are combined with chemotherapy, radiation therapy, surgery, or analgesics. The purpose of this review is to summarize the recently published literature regarding interventional radiology procedures in the treatment of cancer patients with bone metastases, focusing on the efficacy, complications, local disease control and recurrence rate.
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spelling pubmed-92218972022-06-24 Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review Papalexis, Nicolas Parmeggiani, Anna Peta, Giuliano Spinnato, Paolo Miceli, Marco Facchini, Giancarlo Curr Oncol Review Metastases are the main type of malignancy involving bone, which is the third most frequent site of metastatic carcinoma, after lung and liver. Skeletal-related events such as intractable pain, spinal cord compression, and pathologic fractures pose a serious burden on patients’ quality of life. For this reason, mini-invasive treatments for the management of bone metastases were developed with the goal of pain relief and functional status improvement. These techniques include embolization, thermal ablation, electrochemotherapy, cementoplasty, and MRI-guided high-intensity focused ultrasound. In order to achieve durable pain palliation and disease control, mini-invasive procedures are combined with chemotherapy, radiation therapy, surgery, or analgesics. The purpose of this review is to summarize the recently published literature regarding interventional radiology procedures in the treatment of cancer patients with bone metastases, focusing on the efficacy, complications, local disease control and recurrence rate. MDPI 2022-06-07 /pmc/articles/PMC9221897/ /pubmed/35735441 http://dx.doi.org/10.3390/curroncol29060332 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Papalexis, Nicolas
Parmeggiani, Anna
Peta, Giuliano
Spinnato, Paolo
Miceli, Marco
Facchini, Giancarlo
Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review
title Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review
title_full Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review
title_fullStr Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review
title_full_unstemmed Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review
title_short Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review
title_sort minimally invasive interventional procedures for metastatic bone disease: a comprehensive review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221897/
https://www.ncbi.nlm.nih.gov/pubmed/35735441
http://dx.doi.org/10.3390/curroncol29060332
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