Differences in Multicomponent Pharmacokinetics, Tissue Distribution, and Excretion of Tripterygium Glycosides Tablets in Normal and Adriamycin–Induced Nephrotic Syndrome Rat Models and Correlations With Efficacy and Hepatotoxicity

Tripterygium glycosides tablets (TGT) are widely used for treating nephrotic syndrome (NS), but hepatotoxicity is frequently reported. The presence of underlying disease(s) can alter the disposition of drugs and affect their efficacy and toxicity. However, no studies have reported the impact of NS o...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Cheng, Rui, Boucetta, Hamza, Xu, Lei, Pan, Jing–ru, Song, Min, Lu, Yu–ting, Hang, Tai–jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221999/
https://www.ncbi.nlm.nih.gov/pubmed/35754482
http://dx.doi.org/10.3389/fphar.2022.910923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221999/
https://www.ncbi.nlm.nih.gov/pubmed/35754482
http://dx.doi.org/10.3389/fphar.2022.910923

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