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LymphoTrack Is Equally Sensitive as PCR GeneScan and Sanger Sequencing for Detection of Clonal Rearrangements in ALL Patients

Monoclonal rearrangements of immunoglobulin (Ig) genes and T-cell receptor (TCR) genes are used for minimal measurable disease in acute lymphoblastic leukemia (ALL). The golden standard for screening of gene rearrangements in ALL has been PCR GeneScan and Sanger sequencing, which are laborsome and t...

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Detalles Bibliográficos
Autores principales: Paulsen, Karin, Marincevic, Millaray, Cavelier, Lucia, Hollander, Peter, Amini, Rose-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222020/
https://www.ncbi.nlm.nih.gov/pubmed/35741199
http://dx.doi.org/10.3390/diagnostics12061389