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TRK Inhibition with Entrectinib in Metastatic Salivary Secretory Carcinoma (SC): A Case Report

NTRK gene fusions are rare oncogenic driver mutations that can be found in a broad range of neoplasms. In secretory carcinoma (SC), ETV6-NTRK3 gene fusion is seen in a majority of the cases and represents a druggable target for patients with advanced disease in the absence of a currently accepted st...

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Detalles Bibliográficos
Autores principales: Ernst, Matthew S., Lysack, John T., Hyrcza, Martin D., Chandarana, Shamir P., Hao, Desiree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222047/
https://www.ncbi.nlm.nih.gov/pubmed/35735423
http://dx.doi.org/10.3390/curroncol29060314