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Parkin, as a Regulator, Participates in Arsenic Trioxide-Triggered Mitophagy in HeLa Cells

Parkin is a well-established synergistic mediator of mitophagy in dysfunctional mitochondria. Mitochondria are the main target of arsenic trioxide (ATO) cytotoxicity, and the effect of mitophagy on ATO action remains unclear. In this study, we used stable Parkin-expressing (YFP-Parkin) and Parkin lo...

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Detalles Bibliográficos
Autores principales: Zhang, Zhewen, Yi, Juan, Xie, Bei, Chen, Jing, Zhang, Xueyan, Wang, Li, Wang, Jingyu, Hou, Jinxia, Wei, Hulai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222214/
https://www.ncbi.nlm.nih.gov/pubmed/35735630
http://dx.doi.org/10.3390/cimb44060189