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Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer's disease

Introduction: Biomarkers that reflect pathologic processes affecting neuronal function during preclinical and early stages of Alzheimer's disease (AD) are needed to aid drug development. Methods: A targeted, stable isotope, quantitative mass spectrometry‐based investigation of longitudinal chan...

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Detalles Bibliográficos
Autores principales: Libiger, Ondrej, Shaw, Leslie M., Watson, Mark H., Nairn, Angus C., Umaña, Kelly L., Biarnes, Michael C., Canet‐Avilés, Rosa M., Jack, Clifford R., Breton, Yannick‐André, Cortes, Laetitia, Chelsky, Daniel, Spellman, Daniel S., Baker, Susan A., Raghavan, Nandini, Potter, William Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222372/
https://www.ncbi.nlm.nih.gov/pubmed/33984181
http://dx.doi.org/10.1002/alz.12353