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Bioinformatic Prioritization and Functional Annotation of GWAS-Based Candidate Genes for Primary Open-Angle Glaucoma

Background: Primary open-angle glaucoma (POAG) is the most prevalent glaucoma subtype, but its exact etiology is still unknown. In this study, we aimed to prioritize the most likely ‘causal’ genes and identify functional characteristics and underlying biological pathways of POAG candidate genes. Met...

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Detalles Bibliográficos
Autores principales: Asefa, Nigus G., Kamali, Zoha, Pereira, Satyajit, Vaez, Ahmad, Jansonius, Nomdo, Bergen, Arthur A., Snieder, Harold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222386/
https://www.ncbi.nlm.nih.gov/pubmed/35741817
http://dx.doi.org/10.3390/genes13061055